Journal: Journal of neuroscience methods

Article Title: An inexpensive, charge-balanced rodent deep brain stimulation device: a step-by-step guide to its procurement and construction

doi: 10.1016/j.jneumeth.2013.08.003

Figure Lengend Snippet: Design A is designed to be plugged directly into a socket (363 plug, Plastics 1) cemented onto the subjects skull, it has no on/off switch. Switching the device on/off is achieved by shorting the power line switching the device on. Two pins connected by a short wire must be inserted into the contact housing during implantation (pins 1 and 2). The contacts of the stimulating electrodes (E363/6/SP, Plastics 1, pins 5 and 6) and the contacts for the current return path (“ground”) must be inserted into their respective positions in the contact housing (pins 3 and 4). Two contact positions (pins 3 and 4) connect with the battery ground for those using bipolar electrodes (E363/6/SP-2TW, Plastics 1). Only 1 (either will do) of these is necessary for monopolar stimulation referenced to a screw electrode (E363/20/SP, Plastics 1) implanted in the skull. Design B is designed to be carried on a rodent jacket and includes a dedicated on/off switch. Thus fewer connections are required in the electrode pedestal. When ordering the cable the connection diagram must also be sent to Plastics 1 to guarantee the correct connections.

Article Snippet: 10g) while much heavier than a similar commercial stimulation system (TBSI S-Series, 2 channel wireless neural stimulation system, 3.3g) is comparable with heavier recording devices (TBSI W-Series, 126 channel wireless neural recording system, 10g).

Techniques: Battery

Journal: Journal of neuroscience methods

Article Title: An inexpensive, charge-balanced rodent deep brain stimulation device: a step-by-step guide to its procurement and construction

doi: 10.1016/j.jneumeth.2013.08.003

Figure Lengend Snippet: This PCB has a footprint identical the device presented in figure 2. The circuit switches on/off via a miniature slide switch rather than through shorting contacts in the power trace. Thus care must be taken not to encapsulate the switch. (A) 3 channel 363-SL/3 cable (Plastics 1). (B) Device output: the white termination must be connected to ground. The other terminations are the stimulation channels. (C) The output solder pads are nested between the battery connectors. (D) The complete (unencapsulated) device. (E) Devices are prepared for attachment to the small rodent jackets by sticking the hooked side of adhesive hook-and-loop tape to the topmost surface of the device. The looped side of the hook-and-loop tape was stuck to the underside of the device to cushion the battery housings which would otherwise have been adjacent to the animals back. The devices then stick easily to the hook-and-loop material stitched into the rodent jacket. A 10 cent (€) coin is included for scale. Inset: switch positions.

Article Snippet: 10g) while much heavier than a similar commercial stimulation system (TBSI S-Series, 2 channel wireless neural stimulation system, 3.3g) is comparable with heavier recording devices (TBSI W-Series, 126 channel wireless neural recording system, 10g).

Techniques: Battery, Adhesive

Journal: Experimental Neurobiology

Article Title: Desynchronization of Theta Oscillations in Prefrontal Cortex during Self-stimulation of the Medial Forebrain Bundles in Mice

doi: 10.5607/en.2018.27.3.181

Figure Lengend Snippet: Experimental setup and histological verification of the stimulation site. (A) Experimental setup for ICSS. A mouse was positioned in a custom-made stimulation chamber with free access to a wheel. When the mouse turned the wheel by 1/4 of a rotation, a trigger signal from a rotation sensor was sent to both a pulse stimulator and an analog-to-digital (A/D) converter. The pulse stimulator gave the electrical stimulation to the MFB following a protocol arranged in the stimulator. Prefrontal EEG and hippocampal LFP data were acquired by an analog amplifier, digitalized at 500 Hz and recorded by a computer. (B) Histological verification of the tip of the stimulating electrode. CM, central medial thalamic nucleus; ic, internal capsule; mt, mammillothalamic tract; mfb, medial forebrain bundle; 3v, third ventricle.

Article Snippet: A stimulating electrode (2-channel twisted electrode with a 0.3-mm diameter, Plastics One, Roanoke, VA, USA) was implanted in the medial forebrain bundle (MFB) for delivery of the electrical stimulation, and the coordinates were AP −0.34, ML −1.2, DV −5.0.

Techniques: